Zinoviev V V, Vienozhinskis M T, Malygin E G, Nesterenko V F, Popov S G
FEBS Lett. 1984 Mar 12;168(1):166-8. doi: 10.1016/0014-5793(84)80228-8.
The Eco dam methylase is active on denatured DNA and single-stranded synthetic oligonucleotides containing GATC sites. The results suggest that on interaction with single-stranded oligonucleotides the Eco dam methylase is able to form a duplex structure within the GATC site, and that this duplex site is a substrate for enzyme.