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人子宫颈正常、发育异常及肿瘤性鳞状上皮中Ca抗原的免疫组织化学检测

Immunohistochemical detection of Ca antigen in normal, dysplastic and neoplastic squamous epithelia of the human uterine cervix.

作者信息

Lloyd J M, O'Dowd T, Driver M, Tee D E

出版信息

J Clin Pathol. 1984 Jan;37(1):14-9. doi: 10.1136/jcp.37.1.14.

DOI:10.1136/jcp.37.1.14
PMID:6368596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC498610/
Abstract

Immunohistochemical staining was performed on biopsies and cytological samples from normal, dysplastic and neoplastic squamous epithelia using the monoclonal Ca 1 antibody. The results of staining 92 biopsies and 20 cytological samples are described and it is reported that positive staining with Ca 1 antibody was detected in normal, dysplastic and neoplastic epithelia. The role of the Ca 1 antibody in the study of cervical cancer is discussed.

摘要

使用单克隆Ca 1抗体对来自正常、发育异常和肿瘤性鳞状上皮的活检组织和细胞学样本进行免疫组织化学染色。描述了92例活检组织和20例细胞学样本的染色结果，据报道在正常、发育异常和肿瘤性上皮中均检测到Ca 1抗体阳性染色。讨论了Ca 1抗体在宫颈癌研究中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/606e/498610/d5c36cc9be90/jclinpath00172-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/606e/498610/9021636a2505/jclinpath00172-0025-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/606e/498610/f6c16b4966c4/jclinpath00172-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/606e/498610/d5c36cc9be90/jclinpath00172-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/606e/498610/9021636a2505/jclinpath00172-0025-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/606e/498610/f6c16b4966c4/jclinpath00172-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/606e/498610/d5c36cc9be90/jclinpath00172-0027-a.jpg

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引用本文的文献

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Demonstration of an epitope of the transferrin receptor in human cervical epithelium--a potentially useful cell marker.人宫颈上皮中转铁蛋白受体表位的显示——一种潜在有用的细胞标志物。
J Clin Pathol. 1984 Feb;37(2):131-5. doi: 10.1136/jcp.37.2.131.
2
Isolation and chemical and immunochemical characterization of the peanut-lectin-binding glycoprotein from human milk-fat-globule membranes.人乳脂肪球膜中花生凝集素结合糖蛋白的分离及其化学和免疫化学特性分析
Biochem J. 1984 Dec 1;224(2):581-9. doi: 10.1042/bj2240581.
3
Localisation of Ca and HMFG2 antigens in breast tissue by immunoperoxidase, immunofluorescence, and immunoelectron microscopy.

本文引用的文献

1
Cervical carcinoma antigens in the diagnosis of human squamous cell carcinoma of the cervix.宫颈癌抗原在人宫颈鳞状细胞癌诊断中的应用
J Natl Cancer Inst. 1981 Mar;66(3):465-74.
2
A new marker for human cancer cells, 2 immunohistochemical detection of the Ca antigen in human tissues with the Ca1 antibody.一种用于人类癌细胞的新标志物，用Ca1抗体对人体组织中的Ca抗原进行免疫组化检测。
Lancet. 1982 Jul 3;2(8288):7-10. doi: 10.1016/s0140-6736(82)91151-5.
3
A new marker for human cancer cells. 1 The Ca antigen and the Ca1 antibody.一种人类癌细胞的新标志物。1. Ca抗原和Ca1抗体。
通过免疫过氧化物酶、免疫荧光和免疫电子显微镜对乳腺组织中的钙和HMFG2抗原进行定位。
J Clin Pathol. 1985 May;38(5):512-20. doi: 10.1136/jcp.38.5.512.
4
Immunocytochemical reaction of Ca1 and HMFG2 monoclonal antibodies with cells from serous effusions.Ca1和HMFG2单克隆抗体与浆液性积液细胞的免疫细胞化学反应。
J Clin Pathol. 1985 Feb;38(2):180-4. doi: 10.1136/jcp.38.2.180.
5
Distribution of epithelial antigens in the human uterine cervix: a review.人子宫颈上皮抗原的分布：综述
Arch Gynecol Obstet. 1989;246(2):61-84. doi: 10.1007/BF00934123.
Lancet. 1982 Jul 3;2(8288):1-6. doi: 10.1016/s0140-6736(82)91150-3.
4
Centrifugal cytology. I. A quantitative technique for the preparation of glutaraldehyde-fixed cells for the light and scanning electron microscope.离心细胞学。I. 一种用于制备戊二醛固定细胞以用于光学显微镜和扫描电子显微镜观察的定量技术。
J Histochem Cytochem. 1971 Apr;19(4):203-15. doi: 10.1177/19.4.203.