Hägg E, Aström L, Steen L
Acta Med Scand. 1978;203(3):231-5. doi: 10.1111/j.0954-6820.1978.tb14862.x.
This report concerns two patients, a 43-year-old woman and a 53-year-old man, who developed clinical as well as laboratory signs of permanent gonodal and thyroid failure following an acute intracranial infection--in the woman a meningoencephalitis of unknown origin, and in the man an encephalitis caused by Coxsackie B5. Endocrine investigations were compatible with hypothalamic-pituitary dysfunction, with some of the results favoring a hypothalamic lesion. Perhaps hormone deficiency of hypothalamic and/or pituitary origin is a more common sequel of acute meningoencephalitis than has hitherto been reported.
本报告涉及两名患者，一名43岁女性和一名53岁男性，他们在急性颅内感染后出现了永久性性腺和甲状腺功能减退的临床及实验室体征——女性患的是病因不明的脑膜脑炎，男性患的是由柯萨奇B5病毒引起的脑炎。内分泌检查结果符合下丘脑 - 垂体功能障碍，部分结果提示存在下丘脑病变。或许，下丘脑和/或垂体源性激素缺乏作为急性脑膜脑炎的后遗症比迄今报道的更为常见。
