Usvatova I Ia, Speranskaia N V, Sirovskiĭ E B, Amcheslavskiĭ V G, Fokina T V
Zh Vopr Neirokhir Im N N Burdenko. 1984 Jan-Feb(1):10-6.
The response of water-electrolyte metabolism regulating hormones to neurosurgical stress was studied in 54 patients with tumors of the chiasma-sellar area of the brain. Three types of responses of hormones (the activity of renin, aldosterone, cortisol, and vasopressin) were revealed. Type I was characterised by a sharp activation of the hormones studied, type II by an absence of a response, type III by activation of renin and aldosterone and a decrease in vasopressin activity. Responses of types II and III were attended by deep disorders of water-electrolyte balance. The work substantiates the necessity of taking into account the state of the humoral mechanisms of regulation in conducting intensive therapy in neurosurgical patients.
对54例患有脑视交叉 - 鞍区肿瘤的患者，研究了水电解质代谢调节激素对神经外科手术应激的反应。揭示了激素（肾素、醛固酮、皮质醇和血管加压素的活性）的三种反应类型。I型的特征是所研究激素的急剧激活，II型为无反应，III型为肾素和醛固酮激活以及血管加压素活性降低。II型和III型反应伴有水电解质平衡的严重紊乱。该研究证实了在对神经外科患者进行强化治疗时，考虑体液调节机制状态的必要性。
