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胰岛素体外对10日龄Zucker大鼠白色脂肪组织脂肪生成和脂肪酸摄取的影响。

Effects of insulin in vitro on lipogenesis and fatty acid uptake in white adipose tissue of Zucker rats aged 10 days.

作者信息

de Waziers I, Planche E

出版信息

Biochem J. 1984 Mar 1;218(2):653-5. doi: 10.1042/bj2180653.

Abstract

Adipose-tissue lipogenesis and fatty acid uptake in vitro were higher in obese than in lean Zucker rats aged 10 days. On average, insulin stimulated each of these two metabolic pathways to the same extent in both genotypes. However, in fa/fa pups, we observed that insulin stimulation decreased when adipose-tissue weight increased.

摘要

在体外,10日龄肥胖Zucker大鼠的脂肪组织脂肪生成和脂肪酸摄取高于瘦Zucker大鼠。平均而言,胰岛素对这两种代谢途径在两种基因型中的刺激程度相同。然而,在fa/fa幼崽中,我们观察到随着脂肪组织重量增加,胰岛素刺激作用降低。

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