环孢素A用于预防移植物抗宿主病的皮肤学方面。
Dermatological aspects of the use of Cyclosporin A for prophylaxis of graft-versus-host disease.
作者信息
Harper J I, Kendra J R, Desai S, Staughton R C, Barrett A J, Hobbs J R
出版信息
Br J Dermatol. 1984 Apr;110(4):469-74. doi: 10.1111/j.1365-2133.1984.tb04662.x.
Abstract
Oral Cyclosporin A (CyA) was given for the prophylaxis of graft-versus-host disease (GVHD) to sixty-seven patients receiving a bone marrow transplant, and was found to be extremely effective in reducing the severity of acute GVHD. Side-effects of CyA included hypertrichosis, gum hypertrophy, and a rare but serious 'capillary leak' syndrome.
摘要
对67例接受骨髓移植的患者给予口服环孢素A（CyA）预防移植物抗宿主病（GVHD），发现其在减轻急性GVHD严重程度方面极为有效。CyA的副作用包括多毛症、牙龈增生以及一种罕见但严重的“毛细血管渗漏”综合征。
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