Page E H, Wexler D M, Guenther L C
J Am Acad Dermatol. 1986 May;14(5 Pt 1):785-91. doi: 10.1016/s0190-9622(86)70094-7.
Cyclosporin A is a new immunosuppressive agent that selectively affects T helper cells without suppressing the bone marrow. Cyclosporin A has been used primarily to prevent rejection in organ transplantation and acute graft-versus-host disease. Studies suggest that it may be of benefit in psoriasis, pemphigus vulgaris, bullous pemphigoid, Behçet's disease, and collagen vascular disorders. Since cyclosporin A has a potentially important use in dermatology, and since a number of dermatologic side effects are seen as a consequence of its use, it is important that dermatologists be familiar with this drug.
环孢素A是一种新型免疫抑制剂，可选择性地作用于辅助性T细胞而不抑制骨髓。环孢素A主要用于预防器官移植中的排斥反应和急性移植物抗宿主病。研究表明，它可能对银屑病、寻常型天疱疮、大疱性类天疱疮、白塞病和胶原血管疾病有益。由于环孢素A在皮肤病学中有潜在的重要用途，且使用该药会出现一些皮肤方面的副作用，因此皮肤科医生熟悉这种药物很重要。
