Wacha H, Probst M
Chirurg. 1984 Jan;55(1):29-31.
In a prospective, controlled randomised study of 100 patients the healing of the sacral wound after abdomino-perineal exstirpation of the rectum with and without metronidazole parenterally was compared. A significant reduction in hospital stay and in postoperative time of drainage of the sacral wound was found. The primary wound healing, defined as healing without complications within 14 days, was registered in 84% in the treated group and in 56% in the controls. No influence was seen in the number of urinary tract infection by this treatment.
在一项对100例患者进行的前瞻性对照随机研究中，比较了在直肠腹会阴切除术后骶部伤口在接受和未接受甲硝唑胃肠外给药情况下的愈合情况。结果发现住院时间和骶部伤口术后引流时间显著缩短。主要伤口愈合定义为在14天内无并发症愈合，治疗组为84%，对照组为56%。该治疗对尿路感染的数量未见影响。
