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嗜酸性细胞性施奈德乳头状瘤:对鼻窦柱状细胞乳头状瘤的重新评估。

Oncocytic Schneiderian papilloma: a reappraisal of cylindrical cell papilloma of the sinonasal tract.

作者信息

Barnes L, Bedetti C

出版信息

Hum Pathol. 1984 Apr;15(4):344-51. doi: 10.1016/s0046-8177(84)80033-7.

DOI:10.1016/s0046-8177(84)80033-7
PMID:6370825
Abstract

Cylindrical cell papilloma (CCP) is the rarest of three morphologically distinct papillomas that occur in the nose and paranasal sinuses. Because it is unfamiliar to many pathologists, it is often mistaken histologically for papillary adenocarcinoma or even rhinosporidiosis. The clinical and pathologic features of six new cases are reported and compared with those of 14 others reported in the literature. The results of the light microscopic, histochemical, immunocytochemical (cytochrome c oxidase), and ultrastructural studies described here provide conclusive evidence that the swollen, granular, eosinophilic epithelial cells that compose CCP are true oncocytes that arise primarily, or perhaps exclusively, from the respiratory (Schneiderian) epithelium of the sinonasal passages rather than from minor salivary glands. Continued designation of the CCP as such should therefore be discouraged in favor of a more precise term reflecting this derivation. The phrase "oncocytic Schneiderian papilloma" is proposed.

摘要

柱状细胞乳头状瘤(CCP)是发生于鼻腔和鼻窦的三种形态学上不同的乳头状瘤中最罕见的一种。由于许多病理学家对其并不熟悉,在组织学上它常被误诊为乳头状腺癌,甚至鼻孢子虫病。本文报告了6例新病例的临床和病理特征,并与文献中报道的其他14例进行了比较。这里描述的光镜、组织化学、免疫细胞化学(细胞色素c氧化酶)和超微结构研究结果提供了确凿证据,即构成CCP的肿胀、颗粒状、嗜酸性上皮细胞是真正的嗜酸性细胞,主要或可能仅起源于鼻窦通道的呼吸(施耐德)上皮,而非小唾液腺。因此,应避免继续使用CCP这个名称,而采用一个更精确的术语来反映其起源。建议使用“嗜酸性细胞性施耐德乳头状瘤”这一表述。

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