Lynch D P, Newland J R, McClendon J L
J Oral Maxillofac Surg. 1984 Jun;42(6):349-55. doi: 10.1016/s0278-2391(84)80005-1.
Myospherulosis is a unique, inflammatory, granulomatous lesion, which results from the action of lipid substances on extravasated erythrocytes. Petrolatum-based antibiotic ointments are the most frequent etiologic agents of iatrogenically acquired lesions. Six intraoral cases of myospherulosis are presented, including the first reported case in oral soft tissues. The literature of reported cases is summarized and the epidemiology, histopathology, and ultrastructure of the lesions are discussed. Predisposing events and recommendations for future use of petrolatum-based antibiotic ointments are presented.
肌球芽肿病是一种独特的炎症性肉芽肿病变，由脂质物质作用于外渗红细胞所致。凡士林基抗生素软膏是医源性获得性病变最常见的病因。本文报告6例口腔内肌球芽肿病病例，包括口腔软组织中首例报告病例。对已报告病例的文献进行了总结，并讨论了病变的流行病学、组织病理学和超微结构。还介绍了诱发因素以及凡士林基抗生素软膏未来使用的建议。
