Lymphocytic infiltration of the skin (Jessner): a T-cell lymphoproliferative disease.

Recent studies have suggested that Jessner 's lymphocytic infiltration of the skin and lymphocytoma cutis both represent pseudo-B-cell lymphomas. We have now done immunohistochemical studies on frozen skin sections of six patients with lymphocytic infiltration of the skin. In all cases a predominance of T lymphocytes was observed and B lymphocytes were sparse or completely absent. These results indicate that Jessner 's lymphocytic infiltration of the skin is a T-cell lymphoproliferative disease which, unlike lymphocytoma cutis, cannot be regarded as a pseudo-B-cell lymphoma.