Fredrickson B E, Baker D, McHolick W J, Yuan H A, Lubicky J P
J Bone Joint Surg Am. 1984 Jun;66(5):699-707.
We performed a prospective roentgenographic study to determine the incidence of spondylolysis, spondylolisthesis, or both, in 500 unselected first-grade children from 1955 through 1957. The families of the children with spondylolysis were followed in a similar manner. The incidence of spondylolysis at the age of six years was 4.4 per cent and increased to 6 per cent in adulthood. The degree of spondylolisthesis was as much as 28 per cent, and progression of the olisthesis was unusual. The data support the hypothesis that the spondylolytic defect is the result of a defect in the cartilaginous anlage of a vertebra. There is a hereditary pre-disposition to the defect and a strong association with spina bifida occulta. Progression of a slip was unlikely after adolescence and the slip was never symptomatic in the population that we studied.
我们进行了一项前瞻性X线研究，以确定1955年至1957年间500名未经挑选的一年级儿童中椎弓根峡部裂、椎体滑脱或两者皆有的发生率。对患有椎弓根峡部裂的儿童家庭也进行了类似的随访。六岁时椎弓根峡部裂的发生率为4.4%，成年后增至6%。椎体滑脱的程度高达28%，且滑脱进展并不常见。这些数据支持了以下假设：椎弓根峡部裂缺损是椎体软骨原基缺陷的结果。该缺陷存在遗传易感性，且与隐性脊柱裂密切相关。青春期后滑脱进展的可能性不大，在我们研究的人群中，滑脱从未出现症状。
