Moreno A, Salvatella N, De Moragas J M
Med Cutan Ibero Lat Am. 1984;12(2):91-4.
We compared the incidence and morphologic appearance of eosinophilic globules in Spitz's nevi, malignant melanoma and compound nevi. Eosinophilic globules were frequently found in Spitz's nevi, specially in those with junctional or compound features. An statistical significant increase of eosinophilic globules was found in Spitz's nevi when compared with malignant melanoma. Eosinophilic globules are not an reliable criteria for a diagnosis of a bening lesion. The use of multiple histologic parameters for differential diagnosis is necessary.
我们比较了Spitz痣、恶性黑色素瘤和复合痣中嗜酸性小球的发生率和形态学表现。嗜酸性小球在Spitz痣中很常见,特别是在那些具有交界性或复合性特征的痣中。与恶性黑色素瘤相比,Spitz痣中嗜酸性小球的数量有统计学意义的增加。嗜酸性小球不是诊断良性病变的可靠标准。使用多种组织学参数进行鉴别诊断是必要的。