Torres Cortijo A, Man A, Ferradas R
Med Cutan Ibero Lat Am. 1984;12(2):99-105.
Seven cases of DIC with cutaneous manifestations which permitted us to make the diagnosis. Etiopathogenic references are cited and the dermatological literature pointing out especially the cutaneous lesions with their clinical characteristics: ecchymoses which usually evolve to necrosis, bullae, petechiae, hematomas, cyanosis and bleeding at injection sites, and histological: Fibrinous thrombosis of the vessels of the dermis, with hemorrhages, necrosis and dermoepidermic bullae, with slight or no inflammation . In some of these cases the dermatological lesions antedated the characteristic laboratory data.
七例伴有皮肤表现的弥散性血管内凝血(DIC)病例使我们能够做出诊断。文中引用了病因学参考文献,并提及皮肤病变及其临床特征的皮肤病学文献:瘀斑通常发展为坏死、大疱、瘀点、血肿、发绀以及注射部位出血,组织学表现为:真皮血管内纤维蛋白血栓形成,伴有出血、坏死及真皮表皮大疱,炎症轻微或无炎症。在其中一些病例中,皮肤病变早于典型的实验室检查数据出现。