氯泼尼醇在哮喘患者中的长期研究。

Long-term study of cloprednol in asthmatic patients.

作者信息

Miskovits G, Toth A, Parrott D

出版信息

Respiration. 1984;45(2):147-53. doi: 10.1159/000194611.

DOI:10.1159/000194611

Abstract

Cloprednol was used in 18 steroid-dependent patients with chronic reversible bronchial obstruction over a period of 2 years with respect to HPA-axis function and effect on their clinical status. Patients were treated with a single morning dose of 5-12.5 mg orally. 16 patients were maintained clinically satisfactorily with little change in their steroid status. It was concluded that cloprednol was a satisfactory oral steroid in this group of patients when given as a one-daily morning dose.

摘要

在2年的时间里，对18例患有慢性可逆性支气管阻塞的类固醇依赖患者使用氯泼尼醇，观察其对下丘脑-垂体-肾上腺（HPA）轴功能以及临床状况的影响。患者每天早晨口服一次，剂量为5-12.5毫克。16例患者的临床状况维持良好，类固醇状态变化不大。得出的结论是，对于这组患者，氯泼尼醇作为每日一次的早晨剂量口服时是一种令人满意的类固醇药物。