Allen A, Cunliffe W J, Pearson J P, Sellers L A, Ward R
Scand J Gastroenterol Suppl. 1984;93:101-13.
Mucus is secreted throughout the gastrointestinal tract. The primary secretion is the water insoluble gel adherent to the mucosal surface but substantial amounts of mucus also occur in the lumen. The following are discussed: the functions of mucus; the structure and properties of mucus; study of the adherent mucus gel on the mucosal surface; the effects on mucus properties of proteolysis; thiol agents; bile salts; acid and hyperosmolar solutions. Much of our work on mucus has been with that from the stomach but where possible studies on the intestines and colon are discussed. Studies show that mucous secretions from the different regions of the gastrointestinal tract have similar rheological properties although the component glycoproteins differ in their detailed structure.
黏液在整个胃肠道中分泌。主要分泌物是附着在黏膜表面的水不溶性凝胶,但大量黏液也存在于管腔中。以下内容将被讨论:黏液的功能;黏液的结构和特性;对黏膜表面附着黏液凝胶的研究;蛋白水解、硫醇试剂、胆汁盐、酸和高渗溶液对黏液特性的影响。我们关于黏液的许多研究工作都集中在胃黏液上,但在可能的情况下也会讨论对小肠和结肠的研究。研究表明,胃肠道不同区域的黏液分泌物具有相似的流变学特性,尽管其组成糖蛋白的详细结构有所不同。