Takeuchi H, Tomoyoshi T
Hinyokika Kiyo. 1983 Mar;29(3):293-6.
The in vivo solubility of struvite stones experimentally induced in rats was investigated. The struvite stones implanted into bladders of normal rats were reduced in weight; and, they were dissolved by oral administration of ammonium chloride. Cefmetazone cured pyelonephritis and dissolved the bladder stones when it was administered to rats with urinary tract infection caused by Proteus mirabilis. Normalization of urine by antibiotics and acidifying agents may dissolve struvite stones, and help treat infection stones.
研究了实验诱导的大鼠体内鸟粪石结石的溶解度。植入正常大鼠膀胱的鸟粪石结石重量减轻；并且，通过口服氯化铵可使其溶解。当给患有奇异变形杆菌引起的尿路感染的大鼠施用头孢美唑时，它治愈了肾盂肾炎并溶解了膀胱结石。使用抗生素和酸化剂使尿液正常化可能会溶解鸟粪石结石，并有助于治疗感染性结石。
