Sievers H, von Domarus D
Am J Ophthalmol. 1984 Jun;97(6):743-51. doi: 10.1016/0002-9394(84)90507-5.
We studied five intraocular lens implants removed for various reasons by light, transmission, and scanning electron microscopy. Four implants were Binkhorst four-loop lenses; the fifth was of an unidentified type. The durations of implantation ranged from three to 36 months, with an average of 14 months. The surface of all implants was covered with a thin acellular membrane of unknown nature. On top of this membrane we found different types of cells that are normally involved in a foreign-body reaction. These included fibroblasts, histiocytes, epithelioid cells, and multinucleated foreign-body giant cells, in all stages. Our findings suggested that iris-fixed artificial lenses are subject to a defensive cellular reaction by the host. The limited extent of this reaction was correlated with the success of the implant.
我们通过光学显微镜、透射电子显微镜和扫描电子显微镜研究了因各种原因取出的5个人工晶状体植入物。4个植入物是Binkhorst四环晶状体；第5个是不明类型的。植入时间从3个月到36个月不等，平均为14个月。所有植入物的表面都覆盖着一层性质不明的薄无细胞膜。在这层膜上，我们发现了通常参与异物反应的不同类型细胞。这些细胞包括处于各个阶段的成纤维细胞、组织细胞、上皮样细胞和多核异物巨细胞。我们的研究结果表明，虹膜固定人工晶状体受到宿主的防御性细胞反应。这种反应的有限程度与植入物的成功相关。
