Bertschinger H U, Jucker H, Pfirter H P, Pohlenz J
Ann Rech Vet. 1983;14(4):469-72.
The role of nutrition in the pathogenesis of E. coli enterotoxaemia was studied in weaned pigs inoculated with a field strain of E. coli O139:K82(B):H 4. Feeds extremely low in nutrients (5% crude protein, 4.6 MJ/kg digestible energy, 17% crude fibre) completely prevented the disease by inhibiting proliferation of the pathogenic bacteria in the intestine. This protective effect of the diet could not be used for disease control, because the pigs did not develop immunity. A diet moderately low in nutrients (8% crude protein, 9 MJ/kg digestible energy, 11% crude fibre) allowed proliferation of the inoculated bacteria to the point, where most of the pigs developed solid immunity and losses were significantly reduced. This diet combined with inoculation of the pigs with herd specific organisms allowed control of the disease in the field.
在接种大肠杆菌O139:K82(B):H 4田间菌株的断奶仔猪中，研究了营养在大肠杆菌肠毒血症发病机制中的作用。营养成分极低的饲料（粗蛋白5%、可消化能量4.6兆焦/千克、粗纤维17%）通过抑制肠道中病原菌的增殖，完全预防了该病。这种日粮的保护作用不能用于疾病控制，因为猪没有产生免疫力。营养成分适度低的日粮（粗蛋白8%、可消化能量9兆焦/千克、粗纤维11%）使接种的细菌增殖到一定程度，此时大多数猪产生了牢固的免疫力，损失显著减少。这种日粮与用畜群特异性微生物接种猪相结合，可在田间控制该病。
