Stillman R M, Marino C A, Seligman S J
Arch Surg. 1984 Jul;119(7):821-2. doi: 10.1001/archsurg.1984.01390190061013.
In potentially contaminated surgical procedures, wound infection is more likely when percutaneous sutures are used rather than skin tapes. Our reluctance to use tapes routinely because of variability in their adhesive properties prompted this evaluation of the ability of skin staples to resist abscess formation after contamination of the subcutaneous space. In each of 180 mice, a predetermined quantity of Staphylococcus aureus was injected into the subcutaneous space of a fresh skin incision. Closure with the skin stapler was most resistant to abscess formation. Presumably, percutaneous sutures provide a nidus for bacterial growth in the relatively avascular subcutaneous space. This problem is avoided by the use of skin tapes or staples. For those who are insecure about the strength of a closure with skin tapes, the skin stapler should provide an alternative in potentially contaminated cases where delayed primary closure is not elected.
在可能受到污染的外科手术中，使用经皮缝合线时伤口感染的可能性比使用皮肤胶带更大。由于皮肤胶带粘性的变异性，我们不愿常规使用胶带，这促使我们评估皮肤钉合器在皮下间隙受污染后抵抗脓肿形成的能力。在180只小鼠中，每只小鼠在新鲜皮肤切口的皮下间隙注射预定数量的金黄色葡萄球菌。使用皮肤钉合器闭合最能抵抗脓肿形成。据推测，经皮缝合线在相对无血管的皮下间隙为细菌生长提供了病灶。使用皮肤胶带或钉合器可避免这个问题。对于那些对皮肤胶带闭合强度不放心的人来说，在不选择延迟一期缝合的可能受污染的病例中，皮肤钉合器应可提供一种替代方法。
