静脉输注胰岛素对糖尿病患者心肌梗死后死亡率的影响。
Effect of intravenous insulin infusion on mortality among diabetic patients after myocardial infarction.
作者信息
Gwilt D J, Petri M, Lamb P, Nattrass M, Pentecost B L
出版信息
Br Heart J. 1984 Jun;51(6):626-30. doi: 10.1136/hrt.51.6.626.
Abstract
A review of the records of 353 diabetic patients after a myocardial infarction confirmed the high mortality associated with the condition. The influence of improved diabetic control achieved by intravenous insulin was assessed in 64 patients and compared with earlier experience in a diabetic control group. The frequency of the major complications of myocardial infarction was unchanged and the death rate in both groups was identical (33%); even the patients with blood glucose concentrations greater than 20 mmol/l on admission failed to benefit. Thus careful control of blood glucose concentrations after myocardial infarction in diabetic patients fails to improve the outcome of this high risk group.
摘要
对353例心肌梗死后糖尿病患者的记录进行回顾，证实了该疾病相关的高死亡率。对64例患者评估了静脉注射胰岛素实现的糖尿病控制改善情况，并与糖尿病对照组的早期经验进行了比较。心肌梗死主要并发症的发生率没有变化，两组的死亡率相同（33%）；即使入院时血糖浓度高于20 mmol/L的患者也未从中获益。因此，糖尿病患者心肌梗死后仔细控制血糖浓度并不能改善这一高危群体的预后。
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