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免疫反应性脑啡肽在大鼠新纹状体γ-氨基丁酸合成神经元中的定位。

Localization of immunoreactive enkephalins in GABA synthesizing neurons of the rat neostriatum.

作者信息

Aronin N, Difiglia M, Graveland G A, Schwartz W J, Wu J Y

出版信息

Brain Res. 1984 May 23;300(2):376-80. doi: 10.1016/0006-8993(84)90850-3.

DOI:10.1016/0006-8993(84)90850-3
PMID:6375810
Abstract

The localization of immunoreactive glutamic acid decarboxylase (GAD) and enkephalin-like immunoreactivity was examined in serial, 4-micron frozen sections of the caudate nucleus from rats pretreated with colchicine. Colocalization was found in numerous caudate neurons of medium size. Cell counts of corresponding labeled neurons in paired adjacent sections showed that GAD and enkephalin-like immunoreactivity coexist in about one half of the caudate cell populations containing each of these substances.

摘要

在秋水仙碱预处理的大鼠尾状核连续4微米冰冻切片中,检测了免疫反应性谷氨酸脱羧酶(GAD)和脑啡肽样免疫反应性的定位。在许多中等大小的尾状核神经元中发现了共定位。对配对相邻切片中相应标记神经元的细胞计数表明,GAD和脑啡肽样免疫反应性在含有这些物质的大约一半尾状核细胞群体中共存。

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