Taylor R, Proctor S J, James O, Clark F, George K, Alberti M M
Clin Sci (Lond). 1984 Jul;67(1):139-42. doi: 10.1042/cs0670139.
The assumption that insulin binding to monocytes reflects that of insulin binding to adipocytes has been examined. In normal, diabetic, thyrotoxic and cirrhotic subjects no correlation was observed between monocyte and adipocyte insulin binding. Extrapolation is not justified from monocyte binding data to conclusions about insulin-sensitive tissues.
胰岛素与单核细胞的结合反映胰岛素与脂肪细胞的结合这一假设已得到检验。在正常、糖尿病、甲状腺毒症和肝硬化受试者中,未观察到单核细胞与脂肪细胞胰岛素结合之间的相关性。从单核细胞结合数据推断关于胰岛素敏感组织的结论是不合理的。