Griffin F M
Contemp Top Immunobiol. 1984;13:57-70. doi: 10.1007/978-1-4757-1445-6_3.
Macrophage complement receptors, while innately incapable of promoting phagocytosis, can be activated to do so by a number of inflammatory stimuli and by several immunologic mechanisms. Studies with a complement receptor-activating lymphokine reveal that activation occurs as a result of mobilization of innately immobile receptors and suggest that receptor mobility is a prerequisite for phagocytosis. Since Fc receptors are susceptible to blockade by immune complexes at inflammatory sites, phagocytosis mediated by macrophage complement receptors may be of prime importance in vivo.
巨噬细胞补体受体虽然天生就无法促进吞噬作用，但可通过多种炎症刺激和几种免疫机制被激活来发挥这一作用。对一种补体受体激活淋巴因子的研究表明，激活是由于原本静止不动的受体发生动员所致，这表明受体的可移动性是吞噬作用的一个先决条件。由于Fc受体在炎症部位易受免疫复合物的阻断，巨噬细胞补体受体介导的吞噬作用在体内可能至关重要。
