Coughlin C, Greenwald E S, Schraft W C, Grossman S
Arch Intern Med. 1978 Apr;138(4):590-2.
Two patients had both multiple myeloma and myelofibrosis. One, who had both conditions, had autopsy confirmation of diagnosis three months later. The typical picture of agnogenic myeloid metasplasia with myelofibrosis developed in the second patient almost four years after the onset of k light chain myeloma. At this time all evidence of multiple myeloma had disappeared perhaps related to cyclophosphamide therapy. We were able to find two similar cases described in the English language literature. The two conditions may be related.
两名患者同时患有多发性骨髓瘤和骨髓纤维化。其中一名同时患有这两种疾病的患者在三个月后经尸检确诊。第二名患者在κ轻链骨髓瘤发病近四年后出现了典型的特发性髓样化生伴骨髓纤维化的表现。此时，多发性骨髓瘤的所有证据可能都已消失，这可能与环磷酰胺治疗有关。我们在英文文献中找到了两例类似病例。这两种疾病可能有关联。
