Besson-Léaud M, Prat J J, Lavaud J, Ghnassia J C, Bonissol C, Berche P, Cloup M
Arch Fr Pediatr. 1978 Feb;35(2):130-43.
A distal bronchial brushing was performed in 25 children having severe lung diseases. The age of the patients ranged from 7 days to 14 years. Seventeen children were immuno-depressed. Bacteria were isolated five times (2 Staphylococcus aureus, 1 Streptococcus pneumoniae, 1 Serratia marcenscens, 1 Acinetobacter lwoffi), viruses twice (cytomegalovirus, syncytial respiratory virus), Pneumocystis carinii, four times. Cytologic study revealed malignant cells, and cells with intranuclear inclusions, evoking a viral infection. This procedure appears to be harmless in children over 2 years of age. In younger children there is a risk of pneumothorax. the principal indication for distal bronchial brushing is lung disease in immuno-depressed children. It may, however, also be useful in prolonged, treatment-resistant, severe lung diseases.
对25名患有严重肺部疾病的儿童进行了远端支气管刷检。患者年龄从7天至14岁不等。17名儿童免疫功能低下。分离出细菌5次（2次为金黄色葡萄球菌、1次为肺炎链球菌、1次为粘质沙雷氏菌、1次为洛菲不动杆菌），病毒2次（巨细胞病毒、呼吸道合胞病毒），卡氏肺孢子虫4次。细胞学研究发现了恶性细胞以及有核内包涵体的细胞，提示病毒感染。该操作对2岁以上儿童似乎无害。对年幼儿童有气胸风险。远端支气管刷检的主要适应证是免疫功能低下儿童的肺部疾病。然而，它对迁延不愈、治疗抵抗的严重肺部疾病可能也有用。
