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Inhibition of fatty acid synthesis by RMI 14,514 (5-tetradecyloxy-2-furoic acid).

作者信息

Kariya T, Wille L J

出版信息

Biochem Biophys Res Commun. 1978 Feb 28;80(4):1022-4. doi: 10.1016/0006-291x(78)91347-5.

DOI:10.1016/0006-291x(78)91347-5
PMID:637858
Abstract
摘要

相似文献

1
Inhibition of fatty acid synthesis by RMI 14,514 (5-tetradecyloxy-2-furoic acid).RMI 14,514（5-十四烷氧基-2-呋喃甲酸）对脂肪酸合成的抑制作用。
Biochem Biophys Res Commun. 1978 Feb 28;80(4):1022-4. doi: 10.1016/0006-291x(78)91347-5.
2
Mechanism responsible for 5-(tetradecyloxy)-2-furoic acid inhibition of hepatic lipogenesis.5-（十四烷氧基）-2-呋喃甲酸抑制肝脏脂肪生成的作用机制。
J Biol Chem. 1979 Oct 25;254(20):10095-101.
3
In support of the roles of malonyl-CoA and carnitine acyltransferase I in the regulation of hepatic fatty acid oxidation and ketogenesis.支持丙二酰辅酶A和肉碱脂酰转移酶I在调节肝脏脂肪酸氧化和酮体生成中的作用。
J Biol Chem. 1979 Sep 10;254(17):8163-8.
4
Inhibition by 5-(tetradecyloxy)-2-furoic acid of fatty acid and cholesterol synthesis in isolated rat hepatocytes.5-（十四烷氧基）-2-呋喃甲酸对离体大鼠肝细胞脂肪酸和胆固醇合成的抑制作用。
Lipids. 1977 Oct;12(10):814-8. doi: 10.1007/BF02533270.
5
5-(Tetradecyloxy)-2-furoic acid.5-（十四烷氧基）-2-呋喃甲酸
Methods Enzymol. 1981;72:552-9. doi: 10.1016/s0076-6879(81)72043-3.
6
Reciprocal effects of 5-(tetradecyloxy)-2-furoic acid on fatty acid oxidation.5-（十四烷氧基）-2-呋喃甲酸对脂肪酸氧化的相互作用
Arch Biochem Biophys. 1985 Oct;242(1):23-31. doi: 10.1016/0003-9861(85)90475-8.
7
[Activities of 3-hydroxy-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and rate of biosynthesis of mevalonic acid, squalene, sterols and fatty acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: changes induced by daily rhythm].[大鼠肝脏中3-羟基-3-甲基戊二酰辅酶A还原酶和乙酰辅酶A羧化酶的活性以及由[1-¹⁴C]乙酰辅酶A和[2-¹⁴C]丙二酰辅酶A合成甲羟戊酸、角鲨烯、甾醇和脂肪酸的速率：昼夜节律引起的变化]
Biokhimiia. 1981 Jan;46(1):126-39.
8
Inhibition of fatty acid synthesis in isolated adipocytes by 5-(tetradecyloxy)-2-furoic acid.5-（十四烷氧基）-2-呋喃甲酸对分离的脂肪细胞中脂肪酸合成的抑制作用。
Lipids. 1984 Nov;19(11):851-6. doi: 10.1007/BF02534514.
9
5-(Tetradecyloxy)-2-furancarboxylic acid and related hypolipidemic fatty acid-like alkyloxyarylcarboxylic acids.5-（十四烷氧基）-2-呋喃羧酸及相关的降血脂脂肪酸样烷氧基芳基羧酸
J Med Chem. 1977 Jun;20(6):781-91. doi: 10.1021/jm00216a009.
10
[Activities of 3-hydroxyl-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and the rate of mevalonic acid, squalene, sterol and fatty acid biosynthesis from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: effects of Triton WR 1339, starvation and cholesterol diet].[大鼠肝脏中3-羟基-3-甲基戊二酰辅酶A还原酶和乙酰辅酶A羧化酶的活性以及[1-¹⁴C]乙酰辅酶A和[2-¹⁴C]丙二酰辅酶A生成甲羟戊酸、角鲨烯、固醇和脂肪酸的生物合成速率：曲拉通WR 1339、饥饿和胆固醇饮食的影响]
Biokhimiia. 1981 Feb;46(2):296-305.

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Berberine Regulated Lipid Metabolism in the Presence of C75, Compound C, and TOFA in Breast Cancer Cell Line MCF-7.小檗碱在乳腺癌细胞系MCF-7中存在C75、化合物C和TOFA的情况下对脂质代谢的调节作用
Evid Based Complement Alternat Med. 2015;2015:396035. doi: 10.1155/2015/396035. Epub 2015 Aug 13.
2
Human cytomegalovirus pUL37x1-induced calcium flux activates PKCα, inducing altered cell shape and accumulation of cytoplasmic vesicles.人巨细胞病毒 pUL37x1 诱导的钙流激活蛋白激酶 Cα，导致细胞形态改变和细胞质囊泡积累。
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Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication.
人巨细胞病毒诱导乙酰辅酶 A 羧化酶的活性和表达，该酶是一种脂肪酸生物合成酶，其抑制可减弱病毒复制。
J Virol. 2011 Jun;85(12):5814-24. doi: 10.1128/JVI.02630-10. Epub 2011 Apr 6.
4
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy.系统水平的代谢通量分析确定脂肪酸合成作为抗病毒治疗的靶点。
Nat Biotechnol. 2008 Oct;26(10):1179-86. doi: 10.1038/nbt.1500. Epub 2008 Sep 28.
5
Inhibition of fatty acid synthesis in isolated adipocytes by 5-(tetradecyloxy)-2-furoic acid.5-（十四烷氧基）-2-呋喃甲酸对分离的脂肪细胞中脂肪酸合成的抑制作用。
Lipids. 1984 Nov;19(11):851-6. doi: 10.1007/BF02534514.
6
Evidence for a reciprocal relationship between lipogenesis and ketogenesis in hepatocytes from fed virgin and lactating rats.关于进食状态下未孕大鼠和泌乳大鼠肝细胞中脂肪生成与酮体生成之间相互关系的证据。
Biochem J. 1978 Oct 15;176(1):331-4. doi: 10.1042/bj1760331.
7
Inhibition of hepatic lipogenesis by 2-tetradecylglycidic acid.2-十四烷基缩水甘油酸对肝脏脂肪生成的抑制作用。
Lipids. 1979 Oct;14(10):880-2. doi: 10.1007/BF02534133.
8
Regulation of ketogenesis during the suckling-weanling transition in the rat. Studies with isolated hepatocytes.大鼠从哺乳到断奶过渡期间生酮作用的调节。原代肝细胞的研究。
Biochem J. 1979 Apr 15;180(1):137-44. doi: 10.1042/bj1800137.