Henoch M J, Batson J W, Baum J
Arthritis Rheum. 1978 Mar;21(2):229-33. doi: 10.1002/art.1780210209.
A detailed survey of 88 children with juvenile rheumatoid arthritis (JRA) was made in an attempt to elucidate characteristics that may participate in the etiologic mechanism. Data from a random pediatric population from the same geographic area were also included for comparisons. The most striking findings were psychosocial factors. Children whose parents were unmarried as a result of divorce, separation, or death comprised 28.4% of the JRA population, compared to 10.6% of the comparison group. In addition, adoption occurred three times more often in the JRA population. Fifty-one percent of these events (divorce, separation, death, or adoption) occurred near the date of onset of the disease.
对88名青少年类风湿性关节炎（JRA）患儿进行了详细调查，以试图阐明可能参与病因机制的特征。还纳入了来自同一地理区域的随机儿科人群的数据进行比较。最显著的发现是心理社会因素。因离婚、分居或死亡导致父母未婚的儿童占JRA人群的28.4%，而对照组为10.6%。此外，JRA人群中收养情况的发生率是对照组的三倍。这些事件（离婚、分居、死亡或收养）中有51%发生在疾病发病日期附近。
