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伯氏疟原虫中5S和5.8S核糖体RNA分子及其基因的鉴定

Identification of 5 S and 5.8 S ribosomal RNA molecules and their genes in Plasmodium berghei.

作者信息

Dame J B, McCutchan T F

出版信息

Mol Biochem Parasitol. 1984 Apr;11:301-7. doi: 10.1016/0166-6851(84)90074-4.

Abstract

The ribosomes of Plasmodium berghei contain two small RNA molecules approximately 150 and 120 bases long. These correspond in size to 5.8 and 5 S RNA molecules found in the cytoplasmic ribosomes of eukaryotic cells. Segments homologous to the 5.8 S RNA are present in each of the four ribosomal RNA gene units. Restriction fragments which span the region between the coding areas of the two major ribosomal RNA molecules hybridize to 5.8 S RNA, indicating that the gene is located between the small and large ribosomal RNA genes. The gene(s) for the 5 S RNA is not associated with any of the four ribosomal RNA gene units.

摘要

伯氏疟原虫的核糖体含有两个小RNA分子,长度分别约为150个碱基和120个碱基。其大小与真核细胞胞质核糖体中的5.8 S和5 S RNA分子相对应。与5.8 S RNA同源的片段存在于四个核糖体RNA基因单元中的每一个中。跨越两个主要核糖体RNA分子编码区域之间区域的限制性片段与5.8 S RNA杂交,表明该基因位于小核糖体RNA基因和大核糖体RNA基因之间。5 S RNA的基因不与四个核糖体RNA基因单元中的任何一个相关联。

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引用本文的文献

1
Two major sequence classes of ribosomal RNA genes in Plasmodium berghei.
Nucleic Acids Res. 1984 Jul 25;12(14):5943-52. doi: 10.1093/nar/12.14.5943.

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