Decroix G, Chastang C, Lebeau B, Fabre C, Lepage T, Rebishung J L, Babo P, Fichet D, Soubrane C, Asselain B
Rev Mal Respir. 1984;1(1):25-30.
Between March 1978 and May 1981, 219 patients suffering from non-small cell primary bronchial carcinoma underwent surgical excision which was intended to be curative. Three weeks later the patients were randomised into two groups: 1. A control group, with no other treatment following excision (110 patients). 2. A non-specific immunotherapy group (109 patients). The immunostimulant used was an aqueous suspension of heat killed mycobacterium smegmatis administered subcutaneously once a month. The trial was analysed on December 1, 1982. There were 117 recurrences and 112 deceased. There was no significant difference as regard survival without relapse or overall survival; all causes of death were included.
1978年3月至1981年5月期间，219例非小细胞原发性支气管癌患者接受了旨在治愈的手术切除。三周后，患者被随机分为两组：1. 对照组，切除术后不接受其他治疗（110例患者）。2. 非特异性免疫治疗组（109例患者）。所使用的免疫刺激剂是热灭活耻垢分枝杆菌的水悬浮液，每月皮下注射一次。该试验于1982年12月1日进行分析。有117例复发和112例死亡。在无复发存活或总存活方面无显著差异；包括所有死亡原因。
