Davis J R, Steinbronn K K, Graham A R, Dawson B V
Am J Clin Pathol. 1984 Sep;82(3):332-5. doi: 10.1093/ajcp/82.3.332.
Monsel's solution applied to biopsy sites causes tissue necrosis that can persist for two weeks and impede reepithelialization. Granulation tissue in the healing phase contains iron pigment residue from the agent. The pigment encrusts upon collagen and is present in siderophages for up to three months. Occasionally pigment or necrotic residues incite a foreign body giant cell reaction. Awareness is recommended in order to avoid confusion. The agent's potential effect upon the basic disease is discussed.
应用于活检部位的孟塞尔溶液会导致组织坏死,这种坏死可持续两周,并阻碍上皮再形成。愈合期的肉芽组织含有该制剂残留的铁色素。色素附着于胶原蛋白上,并在含铁血黄素细胞中存在长达三个月。偶尔,色素或坏死残留物会引发异物巨细胞反应。建议予以关注以避免混淆。文中还讨论了该制剂对基础疾病的潜在影响。