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大鼠视网膜中促肾上腺皮质激素释放因子样免疫反应性神经元

Corticotropin releasing factor-like immunoreactive neurons in the rat retina.

作者信息

Skofitsch G, Jacobowitz D M

出版信息

Brain Res Bull. 1984 May;12(5):539-42. doi: 10.1016/0361-9230(84)90169-2.

DOI:10.1016/0361-9230(84)90169-2
PMID:6380651
Abstract

Corticotropin releasing factor (CRF)-like immunoreactive neurons have been identified in the rat retina by immunohistochemical methods using antisera directed against ovine and rat CRF. CRF-like immunoreactivity was observed in both amacrine and ganglion cells which projected fine varicose processes to the inner plexiform layer of the retina. It is suggested that CRF may play a role in retinal function.

摘要

利用针对绵羊和大鼠促肾上腺皮质激素释放因子(CRF)的抗血清,通过免疫组织化学方法已在大鼠视网膜中鉴定出CRF样免疫反应性神经元。在无长突细胞和神经节细胞中均观察到CRF样免疫反应性,这些细胞向视网膜内丛状层投射出纤细的曲张突起。提示CRF可能在视网膜功能中发挥作用。

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