婴儿期和儿童期血浆肾素活性及非活性浓度的基础水平。

The basal levels of active and inactive plasma renin concentration in infancy and childhood.

作者信息

Fiselier T, Derkx F, Monnens L, Van Munster P, Peer P, Schalekamp M

出版信息

Clin Sci (Lond). 1984 Oct;67(4):383-7. doi: 10.1042/cs0670383.

Abstract

Basal plasma renin activity, active and inactive plasma renin concentration were measured in 89 healthy recumbent children aged between 1 week and 16 years. A significant (P less than 0.001) age-related decrease for active (r = -0.60), inactive (r = -0.59) and total renin concentration (r = -0.66) was observed. After correction for the influence of age, active renin concentration correlated with plasma renin activity (r = 0.81), but not with inactive renin concentration (r = 0.18). The proportions of active and inactive renin were not related to age, and the overall percentage of inactive renin was 79%.

摘要

对89名年龄在1周龄至16岁之间的健康仰卧位儿童测定了基础血浆肾素活性、活性和非活性血浆肾素浓度。观察到活性肾素（r = -0.60）、非活性肾素（r = -0.59）和总肾素浓度（r = -0.66）均有显著的（P小于0.001）与年龄相关的下降。校正年龄影响后，活性肾素浓度与血浆肾素活性相关（r = 0.81），但与非活性肾素浓度无关（r = 0.18）。活性和非活性肾素的比例与年龄无关，非活性肾素的总体百分比为79%。