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糖化血红蛋白:测量与临床应用

Glycosylated haemoglobin: measurement and clinical use.

作者信息

Peacock I

出版信息

J Clin Pathol. 1984 Aug;37(8):841-51. doi: 10.1136/jcp.37.8.841.

Abstract

The discovery, biochemistry, laboratory determination, and clinical application of glycosylated haemoglobins are reviewed. Sources of error are discussed in detail. No single assay method is suitable for all purposes, and in the foreseeable future generally acceptable standards and reference ranges are unlikely to be agreed. Each laboratory must establish its own. Nevertheless, the development of glycosylated haemoglobin assays is an important advance. They offer the best available means of assessing diabetic control.

摘要

本文综述了糖化血红蛋白的发现、生物化学、实验室测定及临床应用。详细讨论了误差来源。没有一种单一的检测方法适用于所有目的,在可预见的未来,普遍可接受的标准和参考范围不太可能达成一致。每个实验室都必须建立自己的标准和参考范围。尽管如此,糖化血红蛋白检测方法的发展仍是一项重要的进展。它们提供了评估糖尿病控制情况的最佳可用手段。

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