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颈动脉内膜切除术中的大隐静脉补片移植术。

Saphenous vein patch grafts in carotid endarterectomy.

作者信息

Little J R, Bryerton B S, Furlan A J

出版信息

J Neurosurg. 1984 Oct;61(4):743-7. doi: 10.3171/jns.1984.61.4.0743.

Abstract

The clinical data and findings on the early postoperative intravenous digital subtraction angiograms (IVDSA's) were studied in 61 patients undergoing 70 consecutive conventional carotid endarterectomies and in 46 patients undergoing 50 consecutive carotid endarterectomies with a saphenous vein patch graft (SVPG). The IVDSA's were considered normal in 50 of 70 conventional carotid endarterectomies and in 46 of 50 carotid endarterectomies with SVPG (p = 0.004). The internal carotid artery (ICA) origin was consistently larger and had a more normal configuration after carotid endarterectomy with SVPG. Ballooning at the endarterectomy site was an uncommon finding and occurred with similar frequency in both groups; that is, after three conventional carotid endarterectomies and two carotid endarterectomies with SVPG. In the conventional group, early symptomatic thrombosis occurred in the ICA in one patient and in the common carotid artery (CCA), ICA, and external carotid artery (ECA) in two patients. Silent ICA occlusion was seen in three patients in the conventional group. There were no occlusions in the SVPG group (p = 0.04). Stenosis at the distal end of the ICA arteriotomy was found after nine conventional carotid endarterectomies, and was mild (less than or equal to 33% reduction in the lumen) in seven patients, moderate (34% to 66%) in one, and severe (greater than or equal to 67%) in one. Mild distal ICA stenosis was seen in one case after carotid endarterectomy with a SVPG (p = 0.03). Stenosis of 33% or less was found at the proximal end of the CCA arteriotomy after two carotid endarterectomies in the conventional group and one carotid endarterectomy in the SVPG group. Four patients in the conventional group suffered a postoperative cerebral infarct and one patient in the SVPG group suffered a postoperative brain-stem infarct (p = 0.28). The authors' findings have led them to routinely use a SVPG in carotid endarterectomy.

摘要

对61例接受70次连续常规颈动脉内膜切除术的患者以及46例接受50次连续大隐静脉补片移植(SVPG)颈动脉内膜切除术的患者的临床资料和术后早期静脉数字减影血管造影(IVDSA)结果进行了研究。在70次常规颈动脉内膜切除术中,50次IVDSA被认为正常;在50次采用SVPG的颈动脉内膜切除术中,46次IVDSA被认为正常(p = 0.004)。采用SVPG进行颈动脉内膜切除术后,颈内动脉(ICA)起始部始终更大且形态更正常。内膜切除部位的膨出是一种不常见的发现,两组出现频率相似;即在3次常规颈动脉内膜切除术后和2次采用SVPG的颈动脉内膜切除术后出现。在常规组中,1例患者的ICA发生早期症状性血栓形成,2例患者的颈总动脉(CCA)、ICA和颈外动脉(ECA)发生血栓形成。常规组有3例患者出现无症状性ICA闭塞。SVPG组未出现闭塞情况(p = 0.04)。9次常规颈动脉内膜切除术后发现ICA动脉切开术远端狭窄,7例患者为轻度(管腔缩小小于或等于33%),1例为中度(34%至66%),1例为重度(大于或等于67%)。1例采用SVPG进行颈动脉内膜切除术后出现轻度远端ICA狭窄(p = 0.03)。常规组2次颈动脉内膜切除术后以及SVPG组1次颈动脉内膜切除术后,CCA动脉切开术近端发现33%或以下的狭窄。常规组有4例患者发生术后脑梗死,SVPG组有1例患者发生术后脑干梗死(p = 0.28)。作者的研究结果使他们在颈动脉内膜切除术中常规使用SVPG。

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