Correlative scanning electron microscopy in gastrointestinal pathology.

Some applications of SEM to the study of gastrointestinal pathology are illustrated and discussed, along with a review of recent literature in this field. Particular emphasis is placed on correlative microscopy, involving, for example, the reprocessing of SEM specimens for LM and TEM, and of LM paraffin blocks for SEM. In terms of diagnosis and prognosis, the relevance of SEM data at present remains quite limited, calling for the further exploration of clinical and diagnostic problems through correlative techniques.