11-去氧前列环素的合成及其抗聚集活性
[Synthesis and anti-aggregating activity of 11-deoxyprostacyclin].
作者信息
Mel'nikova V I, Pivnitskiĭ K K, Kudriashov S A, Geling N G
出版信息
Bioorg Khim. 1983 Jan;9(1):115-7.
PMID:6385994
Abstract
11-Deoxyprostacyclin was prepared in three stages starting from the 11-deoxyprostaglandin F2 alpha methyl ester. 11-Deoxyanalog showed 0,9% of natural prostacyclin potency in inhibition of platelet aggregation.
摘要
11-脱氧前列环素是从11-脱氧前列腺素F2α甲酯开始分三个阶段制备的。11-脱氧类似物在抑制血小板聚集方面显示出天然前列环素效力的0.9%。
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