De Cock K M, Govindarajan S, Redeker A G
JAMA. 1984 Nov 16;252(19):2746-8. doi: 10.1001/jama.252.19.2746.
Two male homosexual patients, one an intravenous (IV) drug abuser, had hepatitis B surface antigen-positive fulminant hepatitis. On the basis of tests for IgM antibody to hepatitis B core antigen (HBcAg) and for IgM and IgG antibodies to delta agent, acute delta hepatitis in chronic hepatitis B infection was diagnosed. The delta agent appeared to have a role in producing fulminant hepatic failure. Accurate diagnosis of fulminant hepatitis may be impossible without recourse to tests for IgM antibody to HBcAg and antibodies to delta agent. Although delta hepatitis in the United States primarily affects IV drug abusers, this infection can also occur in male homosexuals.
两名男性同性恋患者，其中一名是静脉注射毒品者，患有乙型肝炎表面抗原阳性的暴发性肝炎。根据对乙型肝炎核心抗原（HBcAg）的IgM抗体以及对丁型肝炎病毒的IgM和IgG抗体的检测，诊断为慢性乙型肝炎感染中的急性丁型肝炎。丁型肝炎病毒似乎在导致暴发性肝衰竭中起作用。如果不借助对HBcAg的IgM抗体和丁型肝炎病毒抗体的检测，可能无法准确诊断暴发性肝炎。虽然美国的丁型肝炎主要影响静脉注射毒品者，但这种感染也可发生在男性同性恋者中。
