[Relation between concentrations of lipids, carbohydrates, fibrinogen and thyroid hormone and insulin levels in the blood of patients with chronic forms of ischemic heart disease].

Seventy-five patients with chronic coronary heart disease (CHD), aged 41 to 65 years, were studied for levels of triiodothyronine, total and free thyroxin and immunoreactive insulin. Simultaneously, the glucose tolerance test was carried out and blood concentrations of cholesterol, triglycerides, high density lipoprotein cholesterol, fibrinogen and disoluble fibrin were determined. Patients with CHD displayed decreased basal levels of triiodothyronine, total and free thyroxin and increased concentrations of immunoreactive insulin in the blood which was attended with decreased tolerance to glucose. These hormonal disturbances resulted in an elevation in cholesterol, triglycerides and fibrinogen. CHD patients showed an inverse correlation between cholesterol and free thyroxin levels and a direct relationship between triglycerides and immunoreactive insulin.