Peterslund N A, Esmann V, Ipsen J, Christensen K D, Petersen C M
J Antimicrob Chemother. 1984 Aug;14(2):185-9. doi: 10.1093/jac/14.2.185.
In a double-blind randomised trial 40 patients above 60 years old with acute herpes zoster received either 5 mg/kg acyclovir three times daily intravenously or 400 mg acyclovir five times daily orally for five days. Identical results were obtained with respect to duration of pain and rate of healing. Twenty per cent of orally administered acyclovir was absorbed and gave satisfactory concentrations of acyclovir in the vesicular fluid.
在一项双盲随机试验中，40名60岁以上的急性带状疱疹患者，分别接受每日3次静脉注射5mg/kg阿昔洛韦或每日5次口服400mg阿昔洛韦，疗程均为5天。在疼痛持续时间和愈合率方面获得了相同的结果。口服阿昔洛韦的吸收率为20%，水疱液中的阿昔洛韦浓度令人满意。
