Oral acyclovir in herpes zoster.

Zoster is a common disease that may be associated with severe and protracted pain. Antiviral therapy with acyclovir intravenously has been shown to modify the course of the disease and reduce pain during the acute phase. The results of two studies using doses of 400 mg and 800 mg of acyclovir orally are outlined. The data suggest a significant benefit of the higher dose treatment on the course of the illness and the pain.