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睾丸癌肺转移联合化疗与手术治疗的结果

Results of combined chemo-surgical therapy for pulmonary metastases from testicular carcinoma.

作者信息

Bains M S, McCormack P M, Cvitkovic E, Golbey R B, Martini N

出版信息

Cancer. 1978 Mar;41(3):850-3. doi: 10.1002/1097-0142(197803)41:3<850::aid-cncr2820410311>3.0.co;2-y.

Abstract

Between 1966 and 1976, 34 patients had 42 thoracotomies for resection of recurrent or residual metastatic germinal cell carcinoma primary in the testes in addition to chemotherapy. Of the 34, 18 (53%) are alive and well free of evidence of disease from 4 months to 104 months. Systemic chemotherapy of this group of tumors has improved markedly and many patients are now rendered free of disease and are potentially cured. In some however, an occasional pulmonary nodule did not completely respond or recurred after complete disappearance. The surgery was done to remove the last evidence of disease, and to establish the histology of the metastases.

摘要

1966年至1976年间,34例患者接受了42次开胸手术,以切除睾丸原发性复发性或残留转移性生殖细胞癌,术后还进行了化疗。34例患者中,18例(53%)存活且状况良好,在4个月至104个月期间无疾病证据。这类肿瘤的全身化疗有了显著改善,现在许多患者已无疾病,有潜在治愈可能。然而,在一些患者中,偶尔出现的肺部结节并未完全缓解,或在完全消失后复发。进行手术是为了清除最后的疾病证据,并确定转移灶的组织学类型。

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