Dvoretskiĭ D P, Tashliev V A, Nadyrshin R L, Vasil'ev A Iu
Fiziol Zh SSSR Im I M Sechenova. 1984 Dec;70(12):1666-72.
In anesthetized cats, autonomic respiration in the positive intermitting pressure mode induced a decrease of the minute blood volume under conditions of both the closed and the open chest by 24% and 43% resp. The arterial pressure in the major circulation as well as the pressure in the right heart ventricle were decreased insignificantly (by 10-15%). The mechanical respiration sharply increased the ratio: respiratory dead space volume/alveolar volume. To maintain the adequate values of the gaseous and acid-alkaline composition of arterial blood, it was necessary to set a considerably higher respiratory volume of the apparatus as compared with spontaneous breathing. Certain mechanisms of the artificial ventilation effects upon the cardiovascular and respiratory systems, are discussed.
在麻醉猫中,正压间歇通气模式下的自主呼吸在开胸和闭胸条件下分别使每分血容量减少24%和43%。体循环中的动脉压以及右心室压力无明显降低(降低10 - 15%)。机械通气显著增加了呼吸死腔容积/肺泡容积的比值。与自主呼吸相比,为维持动脉血气体和酸碱成分的适宜值,有必要将仪器的呼吸量设置得更高。文中讨论了人工通气对心血管和呼吸系统影响的某些机制。