Dickreuter W, Berger C
Geburtshilfe Frauenheilkd. 1984 Dec;44(12):803-7. doi: 10.1055/s-2008-1036523.
In a prospective trial, 67 women (outpatients and inpatients) with acute symptomatic infection of the lower urinary tract were randomly selected to receive either a single dose of oral co-trimoxazole or conventional five-day therapy with the same drug. Diagnostic and bacteriological problems were investigated. Both regimens showed similar effectiveness with 91% (five-day therapy) and 100% (single-dose therapy) clinical and bacteriological cure. There were no co-trimoxazole-resistant species in vitro and no therapy side effects. As in other studies, we found that in more than one-third of the cases enterococcus was the responsible bacteria for the infection. This is an important finding because of its resistance to cephalosporins.
在一项前瞻性试验中，随机选取67名患有急性症状性下尿路感染的女性（门诊患者和住院患者），让她们接受单剂量口服复方新诺明或相同药物的传统五日疗法。对诊断和细菌学问题进行了调查。两种治疗方案显示出相似的疗效，五日疗法的临床和细菌学治愈率为91%，单剂量疗法为100%。体外没有对复方新诺明耐药的菌种，也没有治疗副作用。与其他研究一样，我们发现超过三分之一的病例中，肠球菌是感染的致病菌。由于其对头孢菌素耐药，这是一个重要发现。
