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[纤维蛋白胶。持续性复发性自发性气胸的一种新治疗技术]

[Fibrin glue. A new treatment technic in persistent recurrent spontaneous pneumothorax].

作者信息

Scheele J, Mühe E, Wopfner F

出版信息

Chirurg. 1978 Apr;49(4):236-43.

PMID:639618
Abstract

The treatment of choice in idiopathic spontaneous pneumothorax is continuous suction drainage by chest tube for 8--10 days. If this method is not successful, i.e., in patients with a persistent or recurrent pneumothorax, an attempt can be made to produce local pleural adhesions by means of a special fibrin glue, especially in patients with poor general condition. This fibrin glue pleurodesis was performed successfully in seven patients, four of them having a persistent, two a recurrent, and one an iatrogenic pneumothorax. Six of them are now, 3--10 months after therapy, without a recurrence and free of discomfort. One patient died 6 days after treatment from a cerebral stroke. Autopsy showed fibrinous adhesions in the area of the upper lobe. Good tissue compatibility was confirmed histologically.

摘要

特发性自发性气胸的首选治疗方法是通过胸管持续负压引流8至10天。如果这种方法不成功,即对于持续性或复发性气胸患者,可尝试使用一种特殊的纤维蛋白胶促使局部胸膜粘连,尤其是对于一般状况较差的患者。七名患者成功进行了这种纤维蛋白胶胸膜固定术,其中四名患有持续性气胸,两名患有复发性气胸,一名患有医源性气胸。现在,其中六名患者在治疗后3至10个月未复发且无不适。一名患者在治疗后6天死于脑卒。尸检显示上叶区域有纤维蛋白粘连。组织学证实具有良好的组织相容性。

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