Lasser A
Dis Colon Rectum. 1978 Jan-Feb;21(1):20-2. doi: 10.1007/BF02586540.
In a series of 1,002 cases of primary colorectal adenocarcinomas diagnosed during a ten-year period there were 62 (6.2%) patients who had two or more primary colorectal adenocarcinomas. Most of the tumors were more than 5 cm away from each other: 27 carcinomas were separated by 6-10 cm, 16 were separated by 11-20 cm, and 12 were separated by more than 20 cm. It is concluded that the incidence of synchronous carcinomas of the colon is sufficiently high to warrant a search by both surgeon and endoscopist for additional tumors some distance from the initial lesion.
在十年期间诊断出的1002例原发性结直肠癌病例系列中,有62例(6.2%)患者患有两个或更多原发性结直肠癌。大多数肿瘤彼此相距超过5厘米:27例癌灶相距6 - 10厘米,16例相距11 - 20厘米,12例相距超过20厘米。结论是,结肠同时性癌的发生率足够高,足以促使外科医生和内镜医生都去寻找距初始病变一定距离处的其他肿瘤。