Eide T J, Schweder T
Gut. 1984 Nov;25(11):1262-7. doi: 10.1136/gut.25.11.1262.
In a necropsy study of 68 men and 36 women with single or multiple adenomas of the large intestine the distribution of all adenomas within the bowel in individual patients was examined. Each adenoma was recorded both by its distance in centimetres from the caecal pole and by the intestinal segment in which it was found. Adenomas in individual patients were shown to occur significantly closer together than expected from the general distribution of adenomas within each age group. The statistically significant, but not very strong effect of clustering may be caused by the existence of one or more fields of the large intestine specific to individuals who have a higher than average propensity for neoplastic development.
在一项对68名男性和36名女性大肠单发或多发腺瘤患者的尸检研究中，对个体患者肠道内所有腺瘤的分布情况进行了检查。每个腺瘤均记录其距盲肠极的厘米数以及所在的肠段。结果显示，个体患者体内的腺瘤比每个年龄组腺瘤的总体分布预期更为紧密地聚集在一起。这种聚集效应具有统计学意义，但不太显著，可能是由于存在一个或多个特定于某些个体的大肠区域，这些个体发生肿瘤的倾向高于平均水平。
