Smith F W, MacLennan F, Abramovich D R, MacGilivray I, Hutchison J M
Magn Reson Imaging. 1984;2(1):57-64. doi: 10.1016/0730-725x(84)90126-7.
In an effort to demonstrate the potential of nuclear magnetic resonance imaging (NMR) in the management of pregnancy, 15 patients in the first trimester and one in the third trimester of pregnancy have been investigated in the Aberdeen University NMR imager. Simple measurements of biparietal diameter and crown-rump length were made from both the NMR images and the ultrasound images on the same day, with good correlation between the two. The NMR data was displayed as inversion recovery, calculated T1, proton density and S1-S2 images. The proton density and S1-S2 images were found to be the most useful for the demonstration of the fetus and for discriminating between placenta and uterus. The calculated T1 data provided accurate quantification of the proton-spin lattice relaxation times of the different tissues, indicating that this measurement may be of use in the study of fetal brain development and placental function. The inversion recovery images showed poor tissue discrimination and were found to be of limited value. The unique information available using NMR and the non-invasive nature of the technique indicated that it should provide a useful method for the investigation of both fetal development and placental function in addition to making basic measurements of fetal size.
为了证明核磁共振成像（NMR）在孕期管理中的潜力，阿伯丁大学的核磁共振成像仪对15名孕早期患者和1名孕晚期患者进行了检查。同一天从核磁共振图像和超声图像上对双顶径和头臀长度进行了简单测量，二者具有良好的相关性。核磁共振数据显示为反转恢复、计算得到的T1、质子密度和S1 - S2图像。发现质子密度和S1 - S2图像对于显示胎儿以及区分胎盘和子宫最为有用。计算得到的T1数据提供了不同组织质子 - 自旋晶格弛豫时间的准确量化，表明该测量可能有助于胎儿脑发育和胎盘功能的研究。反转恢复图像显示出较差的组织辨别能力，价值有限。使用核磁共振可获得的独特信息以及该技术的非侵入性表明，除了对胎儿大小进行基本测量外，它还应为胎儿发育和胎盘功能的研究提供一种有用的方法。
