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细胞内病原体释放——麻风病模型。

Liberated intracellular pathogen--leprosy model.

作者信息

Skinsnes O K, Chang P H, Kuba B A

出版信息

Acta Leprol. 1984 Oct-Dec;2(2-4):195-210.

PMID:6398581
Abstract

Thirty-three mycobacterial strains, 30 by culture and 3 directly from tissues, isolated from lepromatous leprosy and leprosy infected armadillos, were compared by numerial taxonomy and by antibodies from lepromatous patients. An additional 17 strains of the M-A-I-S complex were similarly compared and all strains were compared by rabbit antibodies induced by tissue bacilli from armadillos from culture HZ-15 and by members of the M-A-I-S complex. The results are discussed in terms of the identification of M. leprae against a background of prior long-held hypotheses as to the characteristics of this bacillus.

摘要

从瘤型麻风患者和感染麻风的犰狳中分离出33株分枝杆菌菌株,其中30株通过培养获得,3株直接从组织中分离得到,采用数值分类法并利用瘤型麻风患者的抗体进行比较。另外17株M-A-I-S复合体菌株也进行了类似比较,所有菌株还通过由来自HZ-15培养物的犰狳组织杆菌诱导产生的兔抗体以及M-A-I-S复合体成员进行比较。根据长期以来关于麻风杆菌特征的假设背景,对麻风杆菌的鉴定结果进行了讨论。

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