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[从感染麻风分枝杆菌的犰狳肝脏中分离出的可培养分枝杆菌的脂质组成]

[Lipid composition of cultivable Mycobacteria isolated from livers of armadillos infected by Mycobacterium leprae].

作者信息

Portaels F, Daffé M, Lanéelle M A, Asselineau C

出版信息

Ann Microbiol (Paris). 1984 May-Jun;135A(3):457-65.

PMID:6380370
Abstract

Four bacterial strains isolated from two livers of armadillos experimentally infected with Mycobacterium leprae were studied. Lipids obtained after saponification and methylation and complex lipids obtained by solvent extraction were examined. The presence of mycolates showed that the four strains belonged to the genus Mycobacterium, but the mycolate patterns, identical for the four strains, were different from those of all strains studied so far. Three of these strains contained phthioceranic acids, which were not found in the fourth one. Only the last strain contained mycosides of the C type, while the three others contained a new type of glycolipid. Their content in mycolates and in glycolipids demonstrated a clear-cut difference between these strains, on the one hand, and M. leprae on the other.

摘要

对从两只经实验感染麻风分枝杆菌的犰狳肝脏中分离出的四种细菌菌株进行了研究。对皂化和甲基化后获得的脂质以及通过溶剂萃取获得的复合脂质进行了检测。分枝菌酸的存在表明这四种菌株属于分枝杆菌属,但这四种菌株相同的分枝菌酸模式与迄今为止研究的所有菌株都不同。其中三种菌株含有结核硬脂酸,而在第四种菌株中未发现。只有最后一种菌株含有C型霉菌糖苷,而其他三种含有一种新型糖脂。它们在分枝菌酸和糖脂中的含量表明,一方面这些菌株与麻风分枝杆菌之间存在明显差异。

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